EXOSC10 Antikörper (C-Term)

Produktnummer ABIN2778684

Dieser Anti-EXOSC10 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von EXOSC10 in WB. Geeignet für Human, Maus, Rind (Kuh), Kaninchen, Ratte, Hund, Meerschweinchen, Pferd und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für EXOSC10 Antikörper (C-Term) (ABIN2778684)

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Ratte, Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EXOSC10 Antikörper

Bindungsspezifität: C-Term

Sequenz: ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region region of human EXOSC10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 885 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EXOSC10 Antikörper (ABIN2778684)

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Details zu EXOSC10

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Andere Bezeichnung: EXOSC10

Hintergrund: EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Alias Symbols: PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
Protein Interaction Partner: SUMO2, UBC, SUMO1, RPA3, RPA2, RPA1, NOMO2, EXOSC6, FERMT3, CHPF, LSM2, EXOSC5, FOXRED1, EXOSC4, XRN1, LSM8, B9D1, USP21, UPF2, NOMO1, EXOSC7, DIS3, EXOSC8, IMMT, RUVBL2, EIF3M, TOX4, SSRP1, SKIV2L, LCAT, DXO, ALDH1B1, AICDA, ESR1, EXOSC3, EXOSC9, DIS3L,
Protein Size: 885

Molekulargewicht: 101 kDa

Gen-ID: 5394

NCBI Accession: NM_001001998, NP_001001998

UniProt: Q01780